Description
This dedicated liquid state 600 MHz NMR spectrometer is equipped for assessment of molecular structure and dynamics in dissolved form. The high field strength of this instrument provides both high sensitivity and spectral resolution. This instrument is on standby to perform these liquid state NMR experiments with a cryo probehead, which strongly boosts sensitivity. The instrument is equipped to perform one- and multidimensional homo- and heteronuclear NMR experiments. The use of a SampleJet sample changer allows for high throughput measurements with minimal operator interaction. This equipment is part of the equipment portfolio of Unilever made available for sharing through Shared Research Facilities and is located at MAGNEtic resonance research FacilitY (MAGNEFY).
Technical Details
US+ magnet, 54 mm, 14.1T
600 MHz NMR AVANCE III US+ console
· BLAXH300/100
· BVT 3000 digital
SampleJet with optional sample cooling (5°C) and sample-ring (not cooled) for walkup access
BCU-05 for probe cooling (5 – 80 °C)
Probehead
TCI Cryo probehead 1H, 13C/15N
Applications
- Molecular structural elucidation low- and high molecular weight compounds in liquid state by means of one- and two-dimensional homo- and heteronuclear NMR.
- Assessment of molecular dynamics and interactions (binding). Quantification of low- and high molecular weight compounds in complex mixtures (foods, plant extracts, body fluids)
o Quantification of primary and secondary lipid oxidation products
o Quantification of polysaccharides
o Quantification of primary metabolites in food mixtures and body fluids
o Quantification of (lyso)phospholipids
o Identification and quantification of polyphenols