Description
High-field Nuclear Magnetic Resonance (NMR) spectroscopy allows a non-invasive and quantitative view on molecules. This multi-purpose 700 MHz NMR spectrometer is equipped for assessment of molecular structure and dynamics in both dissolved and (semi-solid) form. The high field strength of this instruments provides both high sensitivity and spectral resolution. A wide range of liquid and solid state NMR experiments can be performed under a wide range of temperatures. The instrument is equipped for one- and multidimensional homo- and heteronuclear NMR experiments for liquid state samples. For (semi-)solid state materials the instrument can perform magic-angle spinning (MAS) as well as static wide line (WL) experiments. This equipment is part of the equipment portfolio of Unilever made available for sharing through Shared Research Facilities and is located at MAGNEtic resonance research FacilitY (MAGNEFY).
Technical Details
- Ascend magnet, 54 mm (narrow bore), 16.44 T
- 700 MHz NMR AVANCEIII HD console
- Triple channel:
- BLAX2H 500/100/250 amplifier system (X 500 W, 1H 100 W, 2H 250 W)
- BLAH1000 1H/19F, 1 kW
- BLAX500
- Grasp II z-gradient accessory (GCU, 10 A)
- BCU II cooling unit
- BCU Extreme cooling unit
- MAS pneumatic unit
- SampleXpress sample changer (60 positions, 5 and 10-mm spinners)
Probeheads
- 5 mm 1H inverse broad (31P-109Ag) band with z-gradients and ATM
- 10 mm broadband (31P-15N) with z-gradient and ATM
- Wideline probe, 5 mm inserts for 2H, 1H (15N-31P)
- DVT 4 mm CPMAS (triple channel 1H/13C/15N) with Efree
- Inverse 1H/13C HRMAS, 2H lock, 4 mm with gradient
Applications
- Molecular structural elucidation and assessment of molecular dynamics of low- and high molecular weight compounds in liquid state by means of one- and two-dimensional homo- and heteronuclear NMR.
- Molecular structural elucidation and assessment of molecular dynamics of low- and high molecular weight compounds in semi-solid (HRMAS) and solid state (CPMAS, Wideline NMR).
- Quantification of low- and high molecular weight compounds in complex mixtures (foods, plant extracts, body fluids).
Complementary Techniques
Mass spectrometry, microscopy